SIGLEC8 rabbit polyclonal antibody Heating & Mixing

archipelagoid.com
$ 154.00
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Description

SIGLEC8 rabbit polyclonal antibody Heating & MixingSpecification Full name SIGLEC8 rabbit polyclonal antibody Alternative names 50 l 100 l Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background Sialic acid binding immunoglobulin (Ig) like lectins, or SIGLECs are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33 like subgroup of SIGLECs, which are localized

Amplification and overexpression of this gene have been observed in several types of human carcinomas

Blocking Steps

abundantly expressed proteins with diverse functions

Alternatively spliced transcript variants have been described for this gene

downstream GPCR signaling pathways

its molecular weight is optimized to 18–23 kDa

required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies

stable at room temperature for months or at -20°C for long-term storage

The protein localizes to cell membranes

such that they either directly regulate gamma-secretase activity or themselves are protease enzymes

Agilent 1050

storage temp

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