Sapitinib (AZD8931) InletSapitinib (AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell free assays, more potent than Gefitinib or Lapatinib against NSCLC cell, 100 fold more selective for the ErbB family than MNK1 and Flt. Phase 2.
3840-XL 1L extractor system
modified impeller assembly for use in magnetically driven
and shows little activity to Flt3
Corning These 60mL PYREX® Buchner funnels have a 40mm diameter coarse porosity fritted disc with a porosity range of 40 to 60µm which is held toward the maximum pore diameter
which facilitates level control
Corning 1L beaker
01 g at the maximum capacity of 10 kg
Corning These 1L PYREX(r) flat bottom boiling flasks have long necks with tooled mouths and take a No
with activity demonstrated in cisplatin-resistant tumors
A unique collection of 2062 inhibitors for high throughput screening (HTS) and high content screening (HCS)
Corning These 12mm diameter PYREX® gas dispersion tubes have an extra coarse porosity (170 to 220µm) fritted disc and are used to disperse or scrub gas in liquids
binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site
