AZD5153 Bottom Sidearm

AZD5153 Bottom SidearmAZD5153 is a potent, selective, and orally available BET BRD4 bromodomain inhibitor with pKi of 8. 3 for BRD4.

Nalidixic acid is a synthetic 1

The innovative construction of PS R2

an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties

-Thujaplicin (

Src and c-Kit

b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2

Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM

Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells

Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L

which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia

Adrenosterone is endogenous steroid hormone that has been promoted as a dietary supplement capable of reducing body fat and increasing muscle mass

an antidiuretic hormone affecting renal water conservation